OK Ben. I will give you an honorary membership of my FanClub. Myself, I just love things that make my life easier or better and at US$39 I still think this is quite a bargain. But I think [B]ram_ei[/B] rather wants Opto22 to implement this sort of functionality for US$Zero Bucks. Good luck with convincing the programmers!
PACProject is a fantastic software suite at a very reasonable price, (PACProject Basic is free!) but I don't think that blocking normal O.S. functionality is something that Opto22 has to assume inside its environment, especially when these types of programs are out there. Some operating systems allow you to easily implement this, but Windows is not one of them. If you are a "Windows Expert", you can actually do it at the registry level, but Disable Key V2.0 actually makes this FUN!
One last alternative solution for ram_ei. DELL portables do include this functionality at a BIOS level, although I don0t think its an option on DELL desktop workstation models.
I much prefer the above utility, which as Ben points out, provides flexibility "to infinity and beyond". You could even set it up differently for different users, just to add another dimension!